The cardiovascular consequences of fatiguing expiratory muscle work in otherwise resting healthy humans

Fatiguing expiratory muscle work in otherwise resting humans elicits an increase sympathetic motor outflow; whether limb blood flow ([Formula: see text]) and leg vascular resistance (LVR) are affected remains unknown. We found that fatiguing resistive loaded breathing (ERL) did not affect group mean [Formula: text] or LVR. However, within-breath oscillations may reflect a sympathetically mediated vasoconstriction was counteracted by transient increases due to the mechanical effects of high intra-abdominal pressure during ERL.